A constellation of symptoms

Depression – a constellation of symptoms

Depression is a common mental disorder affecting a large number of patients globally, and having a wider impact on their friends, families, carers and employers.1 It is a clinically heterogeneous condition, with a generally underestimated variety of symptoms spanning emotional, physical and cognitive domains.2,3 Despite becoming increasingly recognised as a significant component of depression in many patients, cognitive symptoms are often poorly understood in clinical practice.2,3

While a patient must present with either depressed mood or anhedonia to be diagnosed with depression, they may also be experiencing any number of the following symptoms to a greater or lesser extent:2

References

  1. Depression Factsheet. WHO. Available at: http://www.who.int/mediacentre/factsheets/fs369/en/. Accessed July 2015.
  2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Health Disorders. 5th Washington, DC: American Psychiatric Association; 2013.
  3. Jarema M et al. Psychiatr Pol 2014; 48(6): 1105–1116.
  4. Marazziti D et al. Eur J Pharmacol 2010; 626(1): 83–86.
  5. Hammar A, Ardal G. Front Human Neurosci 2009; 3: 26.
  6. Fehnel SE et al. CNS Spectr 2013; 25: 1–10.
  7. McIntyre RS et al. Depress Anxiety 2013; 30(6): 515–527.
  8. Lam RW et al. Can J Psychiatry 2014; 59(12): 649–654.
  9. Lee RSC et al. J Affect Disord 2012; 140: 113–124.
  10. Conradi HJ et al. Psychol Med 2011; 41(6): 1165–1174.
  11. Paykel ES et al. Dialogues Clin Neurosci 2008; 10: 431–437.