Professor Andrea Fagiolini sat down with us at ECNP 2021 to discuss how patient life engagement in a person with schizophrenia is hard to measure in clinical practice as it’s not standardized; however, proxy measures include treatment satisfaction. Secondary outcome measures that capture patient life engagement could be added to clinical trials. It’s important to understand what a patient’s priorities are in terms of treatment satisfaction as individuals differ. Focusing on life engagement, though more time consuming up front, can lead to better long-term outcomes.