At EAN 2022, Henrik Schytz, Associate Professor of Neurology, Denmark Headache Center, Denmark, discussed how medication overuse headache is a huge problem in people with migraine. Here, a vicious cycle can develop wherein more headaches are treated with more acute medication, leading to more headaches. Many patients are not informed about this so do not know the connection between medication overuse and headache development. Medication overuse headache can have a huge impact on migraine intensity and length.